# Purified Cortrophin® Gel (repository corticotropin injection USP) — Patient & Caregiver Site > Purified Cortrophin® Gel (repository corticotropin injection USP) is a prescription medicine manufactured by ANI Pharmaceuticals, Inc. This site is intended for patients and caregivers in the United States. It provides plain-language information about the conditions Cortrophin Gel is approved to treat, how to use it, savings and support through the Cortrophin In Your Corner program, and downloadable patient education materials. Cortrophin Gel is injected under the skin or into the muscle. It is FDA-approved and available only by prescription. Purified Cortrophin Gel is indicated for multiple conditions across rheumatology, neurology, nephrology, ophthalmology, pulmonology, and dermatology. It is a naturally sourced ACTH (adrenocorticotropic hormone) therapy. The Cortrophin In Your Corner (CIYC) program provides copay assistance, patient assistance for uninsured patients, nurse access specialists, and specialty pharmacy support for eligible patients. Manufacturer: ANI Pharmaceuticals, Inc. Patient Website: https://www.cortrophin.com HCP Website: https://www.cortrophinhcp.com Prescribing Information: https://www.cortrophin.com/pdfs/purified-cortrophin-gel-prescribing-information.pdf Patient Support — Cortrophin In Your Corner: 1-800-805-5258 Adverse Event Reporting: 1-800-308-6755 or www.fda.gov/medwatch Job Code: US-CG-2100003 04/2026 ## Pages - [Homepage](https://www.cortrophin.com/): Overview of all approved indications for Cortrophin Gel with condition-specific navigation, understanding ACTH, starting treatment guidance, and Cortrophin In Your Corner support program links. - [Understanding the Potential Role of ACTH](https://www.cortrophin.com/understanding-the-role-of-acth): Plain-language explanation of how Cortrophin Gel may work. ACTH may reduce inflammation by boosting cortisol production and interacting with inflammation-regulating receptors in different parts of the body. The exact way Cortrophin Gel works is not fully known. - [Getting Started with Cortrophin Gel](https://www.cortrophin.com/getting-started-with-cortrophin-gel): Step-by-step injection instructions for patients self-administering Cortrophin Gel using the multi-dose vial or single-dose prefilled syringe. Includes subcutaneous and intramuscular administration guidance, storage instructions, and links to training videos. - [Savings & Support — Cortrophin In Your Corner](https://www.cortrophin.com/savings-and-support): Information about the Cortrophin In Your Corner (CIYC) program including copay assistance (as little as $0 per fill for eligible commercially insured patients), patient assistance program for uninsured patients who meet financial requirements, nurse access specialists, and specialty pharmacy coordination. Call 1-800-805-5258. - [Patient Resources](https://www.cortrophin.com/resources): Downloadable injection guides (vial and PFS), patient brochures by condition in English and Spanish, injection calendar, injection training videos, and patient assistance application. ## Conditions - [Rheumatoid Arthritis (RA) Flares](https://www.cortrophin.com/rheumatoid-arthritis-flares): Cortrophin Gel as short-term add-on therapy for acute episodes or flares of rheumatoid arthritis, including juvenile rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. - [Acute Gouty Arthritis Flares](https://www.cortrophin.com/gouty-arthritis-flares): Cortrophin Gel as short-term add-on therapy for acute episodes or flares of acute gouty arthritis. The only prescription ACTH therapy available for appropriate patients with acute gouty arthritis flares. - [Atopic Dermatitis (Eczema) and Severe Psoriasis](https://www.cortrophin.com/atopic-dermatitis-severe-psoriasis): Cortrophin Gel for treatment of atopic dermatitis (eczema) and severe psoriasis as an additional treatment option for appropriate patients. - [Select Cases of Systemic Lupus Erythematosus (SLE)](https://www.cortrophin.com/select-cases-of-sle): Cortrophin Gel for treatment for flares or as maintenance therapy in select cases of systemic lupus erythematosus (lupus). - [Select Cases of Dermatomyositis (DM) / Polymyositis (PM)](https://www.cortrophin.com/select-cases-of-dm-pm): Cortrophin Gel for treatment for flares or as maintenance therapy in select cases of systemic dermatomyositis (polymyositis). - [Symptomatic Sarcoidosis](https://www.cortrophin.com/symptomatic-sarcoidosis): Cortrophin Gel for treatment of patients with symptoms of sarcoidosis who need an additional treatment option. - [Multiple Sclerosis (MS) Flares](https://www.cortrophin.com/multiple-sclerosis-flares): Cortrophin Gel for acute attacks or flares of multiple sclerosis. - [Excess Protein in the Urine Due to Nephrotic Syndrome](https://www.cortrophin.com/protein-in-the-urine-due-to-nephrotic-syndrome): Cortrophin Gel to reduce protein in the urine (proteinuria) in patients with nephrotic syndrome of the idiopathic type (unknown origin) without uremia, or due to lupus. Includes information for patients with FSGS (focal segmental glomerulosclerosis) and MN (membranous nephropathy). - [Severe Inflammatory Eye Diseases](https://www.cortrophin.com/severe-inflammatory-eye-diseases): Cortrophin Gel for severe acute and chronic allergic and inflammatory conditions affecting different parts of the eye, including iritis, iridocyclitis, uveitis, keratitis, optic neuritis, chorioretinitis, and other conditions. ## Optional - [Full Content Reference (llms-full.txt)](https://www.cortrophin.com/llms-full.txt): Complete patient-facing content reference including all indications, ISI, injection instructions, CIYC program details, and all downloadable resource URLs. - [Sitemap](https://www.cortrophin.com/sitemap): Full site navigation index. - [Prescribing Information (PDF)](https://www.cortrophin.com/pdfs/purified-cortrophin-gel-prescribing-information.pdf): Full FDA-approved prescribing information. - [Vial Injection Guide (PDF)](https://www.cortrophin.com/pdfs/purified-cortrophin-gel-injection-guide.pdf): Step-by-step patient injection guide for the multi-dose vial. - [PFS Injection Guide (PDF)](https://www.cortrophin.com/pdfs/purified-cortrophin-gel-PFS-injection-guide.pdf): Step-by-step patient injection guide for the prefilled syringe. - [Patient Assistance Application (PDF)](https://www.cortrophin.com/pdfs/purified-cortrophin-gel-patient-assistance-application.pdf): Application for uninsured patients who meet financial eligibility requirements.